MPH

MPH (MINQUE for Partitioning Heritability) is a C++ program for fast REML estimation of genetic (co)variance components.

The method has the following properties:

• It is fast and memory-efficient.
• It has robust convergence.
• It supports the analyses of dominance, epistasis, and genetic correlation.
• It can perform complex genome-partitioning of quantitative genetic variation and covariation.

Citation

Jicai Jiang, MPH: fast REML for large-scale genome partitioning of quantitative genetic variation, Bioinformatics, 2024;, btae298, https://doi.org/10.1093/bioinformatics/btae298

License

MPH is distributed under the GPL-3.0 license.

Author and contact

Jicai Jiang

If you want to submit an issue concerning the software, please do so using the MPH GitHub repository.